RADICALS is a large clinical trial which is taking place
in the UK, Canada, Denmark
and the Republic of Ireland at the moment.
It is a phase III randomised controlled trial that will recruit
approximately 3000 men to help answer two important questions for
men who have had surgery for prostate cancer:
- Which is the best way to use radiotherapy after surgery?
- Which is the best way to use hormone treatment with any
radiotherapy given after surgery
In breast cancer, surgery is followed by radiotherapy and
hormone treatment, because the combination is better than surgery
alone. In prostate cancer, surgery alone is a standard
treatment, and we are not sure how best to use radiotherapy and
hormone treatment after surgery.
The trial may be suitable at some point for most men who have a
Read more about
1 July 2015
RADICALS-HD closed on 30th June 2015 with just under
RADICALS-RT is still open to
recruitment so please continue to support us.
22nd May 2014
We are pleased to say that we will continue recruting to both
comparisons in RADICALS-HD until mid-2015 and possibly longer for
Also, everyone should now have all the documents for the
recently approved protocol amendment version 5.0
8th November 2013
Princess Margaret Hospital in Toronto put in their 100th patient
on 30th October 2013! Well done and congratulations for all
your hard work! They now join Guy’s Hospital and Mount Vernon
Hospital in London as the centres with more than 100
patients. We look forward to seeing this list grow.
15th July 2013
We have reached a fantastic milestone in RADICALS-HD where we
now have 1000 patients in each of the two RADICALS-HD comparisons
(none vs short and short vs long). Our target accrual is at least
1370 patients in the none-vs-short comparison and at least 1130
patients in the short-vs-long comparison. Currently we have 1916
patients in RADICALS-HD overall and we are hoping to recruit an
overall total in excess of 2500 patients, so, we still need
everyone to keep up the great work and keep recruiting